New Study States Obesity Makes Pfizer Coronavirus Vaccine Less Effective Confirming Previous Site Claims About The Virus

New Study States Obesity Makes Pfizer Coronavirus Vaccine Less Effective Confirming Previous Site Claims About The Virus

March 4. 2021

Pfizer

A new study in Italy has stated the Pfizer coronavirus vaccine is not as effective on obese people. The study found the efficacy of the Pfizer coronavirus vaccine is significantly less in the obese. The study was conducted on healthcare workers.

This supports my article from 1-YEAR ago, where I was the first to state coronavirus poses a greater risk to the obese than average weight people (Reports Confirm Obesity And Compromised Immune System Linked To Severity Of Coronavirus Infections As Previously Stated On The Site).

Pfizer

When I wrote the article "Reports Confirm Obesity And Compromised Immune System Linked To Severity Of Coronavirus Infections As Previously Stated On The Site" on April 10, 2020 and the tweets contained therein in March 2020, America did not lead the world in coronavirus deaths. However, now America leads the world in coronavirus deaths, with 518,000 people having died due to Covid-19, which further supports my claims, as America also leads the world in obesity.

Please see: 78 People In A Nursing Home Have Contracted Coronavirus And 7 Have Died All AFTER Receiving The Pfizer Coronavirus Vaccine Confirming Previous Site Claims and Male Healthcare Worker Dies Quickly After Receiving SECOND Dose Of Pfizer Coronavirus Vaccine Confirming Previous Site Claims and Michigan Newscaster Dies Right After Receiving Pfizer Coronavirus Vaccine Confirming Previous Site Claims and 78-Year-Old Woman Died Immediately After Receiving Pfizer Coronavirus Vaccine Confirming Previous Site Claims.

STORY SOURCE

Pfizer vaccine may be less effective in people with obesity, says study

Sun 28 Feb 2021 13.18 EST - Healthcare workers with obesity found to produce only about half the antibodies healthy people do. The Pfizer/BioNTech vaccine may be less effective in people with obesity, data suggests.

Italian researchers have discovered that healthcare workers with obesity produced only about half the amount of antibodies in response to a second dose of the jab compared with healthy people. Although it is too soon to know what this means for the efficacy of the vaccine, it might imply that people with obesity need an additional booster dose to ensure they are adequately protected against coronavirus.

Previous research has suggested that obesity – which is defined as having a body mass index (BMI) over 30 – increases the risk of dying of Covid-19 by nearly 50%, as well as increasing the risk of ending up in hospital by 113%.

Some of this may be because people with obesity often have other underlying medical conditions, such as heart disease or type 2 diabetes, that increase their risk from the coronavirus, but excess body fat can also cause metabolic changes, such as insulin resistance and inflammation, which make it harder for the body to fight off infections.

This constant state of low-grade inflammation can also weaken certain immune responses, including those launched by the B and T cells that trigger a protective response following vaccination. Separate research has shown that the flu vaccine is only half as effective in people with obesity compared to those who are a healthy weight. The new study, which has not yet been peer reviewed, provides the first direct evidence to suggest a similar problem might occur with Covid-19 vaccines.

Aldo Venuti, of the Istituti Fisioterapici Ospitalieri in Rome, and his colleagues assessed the antibody response following two doses of the Pfizer/BioNTech vaccine in 248 healthcare workers. Seven days after receiving the second dose, 99.5% of them had developed an antibody response, and this response was greater than that recorded in people who had recovered from Covid-19. However, the response was blunted in people who were overweight and obese.

“Since obesity is a major risk factor for morbidity and mortality for patients with Covid-19, it is mandatory to plan an efficient vaccination programme in this subgroup,” Aldo and his colleagues wrote. “Although further studies are needed, this data may have important implications to the development of vaccination strategies for Covid-19, particularly in obese people. If our data was to be confirmed by larger studies, giving obese people an extra dose of the vaccine or a higher dose could be options to be evaluated in this population.”...

https://www.theguardian.com

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